G6PD screen

Alternative names, keywords

Glucose-6-phosphate dehydrogenase, G6PDH

Samples required

EDTA blood (purple cap/ black cap ring, 4 mL tube). Smaller tubes are available for paediatric samples.

Test indications

Screening for the inherited disorder G6PD deficiency is indicated in investigation of metabolic disorder of the red cells. Test is included as part of investigation for haemolytic anaemia and pre commencement of oxidative drugs.

Reference range

See report. Samples with a deficient screen will require a full G6PD assay to be performed. Full assays are referred (via Worthing Hospital) to the Red Cell Protein Laboratory dept, Haematology, King's College Hospital.

Falsely high G6PD results may be seen after a haemolytic crisis due to increased reticulocytes, which have higher G6PD levels than mature red blood cells. Marked leucocytosis and thrombocytosis can also interfere with the screen and give false normal results.

Turnaround time

Up to 15 working days from receipt of sample at referring laboratory for final report.

Enquiries

Haematology