The diagrams below give an indication of the changes in reference ranges that are expected in pregnancy. Detailed method-specific ranges are not easily obtained; the diagrams use published data* and are not strictly comparable to BSUH ranges due to the use of different methodologies.
*Abbassi-Ghanavati M, Greer LG, Cunningham FG. Pregnancy and laboratory studies: a reference table for clinicians. Obstet Gynecol. 2006;114(6):1326–1331.
Trimester-specific ranges for current BSUH methods are available for thyroid function tests and oestradiol.
KEY | |
BSUH NP |
BSUH range for non-pregnant adult female. |
NP |
Reference range quoted in reference paper for non-pregnant adult female. Note that ranges are not strictly comparable due to the use of different methodologies. For analytes marked *, BSUH units are IU/L, reference paper U/L. |
1st, 2nd and 3rd |
Ranges quoted in the reference paper for the three trimesters of pregnancy. |
U&E, amylase, uric acid, CRP
LFT profile, CK, LDH
Bone profile, magnesium, PTH, ACE
See LFT profile for albumin and ALP |
Cortisol, sex hormones, AFP
Reference data for prolactin and AFP are plotted on secondary axes (in red) as they are in different units to those used by BSUH. Trimester-specific ranges are available for current BSUH thyroid function tests and oestradiol methods.
Lipids
BSUH quotes lipid targets rather than reference ranges: Cholesterol < 5.0 mmol/L HDL >1.0 mmol/L LDL < 3.0 mmol/L Triglycerides < 2.0 mmol/L |