Apixaban

 

Alternative names, keywords

 

Samples required

Trisodium citrate blood (blue cap, 3.5 mL tube) taken with minimal stasis, filled to the line. Smaller tubes are available for paediatric samples.

Immediate transport to the lab is essential. GP surgeries should endeavour to ensure samples are received within this time.

This test can only be added to a request within 2 hours of sample collection. 

Test informaton

It is essential to state whether a peak or trough sample. Please provide information on time of last dose.

Reference range

Apixaban 10mg BD in VTE prevention:

Peak levels 111 - 572 ng/mL

Trough levels 41 - 335 ng/ml

Apixaban 5mg BD:

In stroke prevention:

Peak levels 91 - 321 ng/mL

Trough levels 41 - 230 ng/mL

In VTE prevention:

Peak Levels 59 - 302 ng/mL

Trough levels 22 - 177 ng/mL

Apixaban 2.5mg BD:

In stroke prevention:

Peak levels 69 - 221 ng/mL

Trough levels 34 - 162 ng/mL

In VTE prevention:

Peak Levels 30 - 153 ng/mL

Trough levels 11 - 90 ng/mL

Source: Eliquis 5 mg film-coated tablets, https://www.medicines.org.uk/emc/product/2878/smpc

Turnaround time

Same day.

Enquiries

Haematology (Coagulation)