P1NP

 Referred to Berkshire & Surrey Pathology Services, Frimley Park Hospital NHS Foundation Trust, Portsmouth Road, Frimley, Surrey GU16 7UJ
 

Alternative names, keywords

Procollagen type 1 N-terminal propeptide, procollagen 1, procollagen extension peptide, amino pro-peptide of type 1 collagen.

Samples required

Clotted blood (gold cap, 5 mL tube).

Test indications

Marker of bone formation.

Reference range

Adult female (pre-menopausal): 30 - 78 µg/L
Adult female (post-menopausal): 26 - 110 µg/L
Adult male: 20 - 76 µg/L
 

Bisphosphonate monitoring

Baseline: > 80 µg/L - seek cause of high bone turnover.
Response at 6 months:
Good: < 35 µg/L and/or fall >10 µg/L
Suboptimal: > 35 g/L and fall <10 µg/L
  

Turnaround time

Referral lab quotes turnaround time of 15 days, however additional time must be allowed for packing, dispatch and delivery of sample, and return and processing of results.

Enquiries

Biochemistry (Referrals)