Tobramycin

Alternative names, keywords

Samples required

● Clotted blood (gold cap, 5 mL tube). Smaller tubes are available for paediatric samples.

Please ensure form states whether sample is trough or peak.

For appropriate sampling times please see UHSussex antimicrobial guidelines.

Test indications

Factors affecting test performance/ results

Amikacin cross-reacts with this assay. Kanamycin cross-reacts significantly; however, the assay has not been optimized to quantitate this aminoglycoside. Aminoglycosides are not generally coadministered in clinical practice, although more than one aminoglycoside may be present when switching from treatment with one to another. Samples that contain tobramycin in combination with either amikacin or kanamycin cannot be reliably quantitated by this assay.

In very rare cases, gammopathy, in particular type IgM (Waldenström’s macroglobulinemia), may cause unreliable results.

Results should always be assessed in conjunction with the patient’s medical history, clinical examination and other findings.

Reference range

If detailed interpretation required please discuss with Pharmacy.

Turnaround time

RSCH same day (within 1h if urgent), PRH 24h (4h if urgent).

Enquiries

Biochemistry (Automation)