SHBG

Alternative names, keywords

Sex hormone binding globulin

Samples required

● Clotted blood (gold cap, 5 mL tube). Smaller tubes are available for paediatric samples.

Test indications

Useful for interpretation of total testosterone result. Hirsutism is often associated with a low SHBG and hence increased free testosterone.

Factors affecting test performance/ results

Samples should not be taken from patients receiving therapy with high biotin doses (i.e. > 5 mg/day) until at least 8 hours following the last biotin administration.

In rare cases, interference due to extremely high titres of antibodies to analyte-specific antibodies, streptavidin or ruthenium can occur.

Results should always be assessed in conjunction with the patient’s medical history, clinical examination and other findings.

Reference range

_{Source: Roche Cobas^® Testosterone kit insert 2023-10, V3.0}

Turnaround time

RSCH same day*, PRH two working days

_{*analysis not available at weekends.}

Enquiries

Biochemistry (Automation)