Oestradiol

Alternative names, keywords

E2, estradiol

Samples required

● Clotted blood (gold cap, 5 mL tube). Smaller tubes are available for paediatric samples.

State day of cycle. Test is inaccurate if patient is taking oral hormone replacement.

Test indications

Factors affecting test performance/ results

Erroneous test results may be obtained from samples taken from patients who keep rabbits or have been exposed to vaccines containing rabbit serum.

Due to the risk of cross reactivity causing falsely high results, this assay should not be used when monitoring oestradiol levels in patients being treated with fulvestrant (Faslodex^®). Please contact laboratory to arrange analysis by an alternative method in these patients.

Steroid drugs may interfere with this test.

Samples should not be taken from patients receiving therapy with high biotin doses (i.e. > 5 mg/day) until at least 8 hours following the last biotin administration.

In rare cases, interference due to extremely high titres of antibodies to analyte-specific antibodies, streptavidin or ruthenium can occur.

Results should always be assessed in conjunction with the patient’s medical history, clinical examination and other findings.

Reference range

_{Source: Roche Cobas^® Estradiol kit insert 2023-09, V10.0} 

Turnaround time

RSCH same day*, PRH 2 working days

_{*analysis not available at weekends.}

Enquiries

Biochemistry (Automation)