Lactate (plasma)

Alternative names, keywords

Samples required

● Fluoride oxalate blood (grey cap, 2 mL tube). Smaller tubes are available for paediatric samples.

Please ensure sample is well mixed.

Test indications

Factors affecting test performance/ results

Paracetamol intoxications are frequently treated with N-acetylcysteine. N-acetylcysteine at a plasma concentration above 750 mg/L and the paracetamol metabolite N-acetyl-p-benzoquinone imine (NAPQI) independently may cause falsely low results.

A significant interference (falsely low results) may occur at any plasma metamizole concentration.

Calcium dobesilate causes artificially low lactate results.

Glycolate, a metabolite of ethylene glycol, causes a positive interference which is variable from lot to lot of reagent.

Dicynone (Etamsylate) at therapeutic concentrations may lead to false-low results.

In very rare cases, gammopathy, in particular type IgM (Waldenström’s macroglobulinemia), may cause unreliable results.

Results should always be assessed in conjunction with the patient’s medical history, clinical examination and other findings.

Reference range

0.5 - 2.2 mmol/L
_{Source: Roche Cobas^® Lactate Gen.2 kit insert, 2024-09, V13.0}

Turnaround time

Within 1h if urgent.

Enquiries

Biochemistry (Automation)