Immunoglobulins

 

Alternative names, keywords

IgG, IgA, IgM

Samples required

● Clotted blood (gold cap, 5 mL tube). Smaller tubes are available for paediatric samples.

Test indications

  

Factors affecting test performance/ results

As with other turbidimetric or nephelometric procedures, these tests may not provide accurate results in patients with monoclonal gammopathy, due to the unpredictable characteristics of paraproteins.

Results should always be assessed in conjunction with the patient’s medical history, clinical examination and other findings.

Reference range

Results are only valid if the Ig class is polyclonal (i.e. no paraproteins present).

Adults:

IgG 7 - 16 g/L
IgA 0.7 - 4.0 g/L
IgM 0.4 - 2.3 g/L

 

Paediatric (all in g/L):

IgG 0 to 14 days 3.20 - 12.1
  15 days to <1 year 1.48 - 6.31
  1 to <4 years 3.17 - 9.94
  4 to <10 years 5.01 - 11.7
  10 to <19 years  5.95 - 13.1
     
IgA 0 to <1 year < 0.14
  1 to <3 years < 0.80
  3 - <6 years 0.11 - 1.42
  6 to <14 years 0.34 - 2.20
  14 to <19 years 0.40 - 2.93
     
IgM 0 to 14 days  0.03 - 0.32
  15 days to <13 weeks 0.10 - 0.67
  13 weeks to <1 year 0.14 - 0.82
  1 to <19 years
female: 0.45 - 1.78
male: 0.36 - 1.44

Source: Roche Cobas® IgG kit insert 2024-09, 14.0
Roche Cobas® IgA-2 kit insert 2024-08, V10.0
Roche Cobas® IgM-2 kit insert 2024-07, V11.0

Turnaround time

RSCH same day, PRH within 24h.

Enquiries

Biochemistry (Automation)
 
Details