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Alternative names, keywords |
Cyclosporin, cyclosporine. |
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Samples required |
● EDTA blood (purple cap/ yellow cap ring, 4 mL tube). Smaller tubes are available for paediatric samples. Trough sample required. |
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Test indications |
Ciclosporin monitoring where required. |
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Factors affecting test performance/ results |
Samples should not be taken from patients receiving therapy with high biotin doses (i.e. > 5 mg/day) until at least 8 hours following the last biotin administration. In rare cases, interference due to extremely high titres of antibodies to analyte-specific antibodies, streptavidin or ruthenium can occur. Results should always be assessed in conjunction with the patient’s medical history, clinical examination and other findings. |
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Reference range |
Therapeutic range depends on many factors including clinical picture, individual sensitivity to therapeutic and toxic effects, co-administration of other immunosuppressants, type of transplant and time post-transplant (where applicable). Changes to treatment regimes should not be based solely on individual ciclosporin results. |
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Turnaround time |
Run twice a week, usually on Tuesdays and Fridays. |
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Enquiries |
Biochemistry (Automation) |