Bilirubin (conjugated)

 

Alternative names, keywords

Direct bilirubin

Samples required

Clotted blood (gold cap, 5 mL tube). Smaller tubes are available for paediatric samples.

Avoid haemolysis.

Test indications

 

Factors affecting test performance/ results

Haemolysis may invalidate result.

In certain cases specimens may give a direct bilirubin result slightly greater than the total bilirubin result. This is observed in patient samples when nearly all the reacting bilirubin is in the direct form.

Phenylbutazone causes artificially low bilirubin results.

Samples containing indocyanine green must not be measured.

In very rare cases, gammopathy, in particular type IgM (Waldenström’s macroglobulinemia), may cause unreliable results.

Results should always be assessed in conjunction with the patient’s medical history, clinical examination and other findings.

Reference range

Neonates: < 10 µmol/L*
Adults: 0 - 5 µmol/L

*Limit cited in the literature, although not confirmed with kit manufacturer's data.
Source: Roche Cobas® Direct Bilirubin kit insert 09-2015, V6.0

Turnaround time

Same day (within 1h if urgent)

Enquiries

Biochemistry (Automation)