Alpha-1 antitrypsin (serum)

 

Alternative names, keywords

α1AT, α1 antitrypsin, A1AT

Samples required

Clotted blood (gold cap, 5 mL tube). Smaller tubes are available for paediatric samples.

Test indications

Investigation of suspected alpha-1 antitrypsin deficiency.

Reference range

Adults: 0.9 - 2.0 g/L

Paediatric:

Birth

 0.9 - 2.2 g/L

6 months

 0.8 - 1.8 g/L

1 year

 1.1 - 2.0 g/L

5 years

 1.1 - 2.2 g/L

10 years

 1.4 - 2.3 g/L

15 years

 1.2 - 2.0 g/L

>15 years

 as adult

 

Samples with an alpha-1 antitrypsin concentration of less than 1.2 g/L are routinely referred for alpha-1 antitrypsin phenotyping.

Note that alpha-1 antitrypsin deficiency may be masked in inflammation/infection, pregnancy and exogenous hormone use.

Turnaround time

2 working days

Enquiries

Biochemistry (Special Chemistry)

 

Details